MBC
1-环丙基-6-氟-4-氧代-7-(哌嗪-1-基)-1,4-二氢喹啉-3-羧酸|Ciprofloxacin
| PB00748-1g
純度: 98%
M0703-83841
PB00748-1g
1g
85721-33-1
C17H18FN3O3
98%
¥35.00
¥30.00
1
3 天
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昀冠品质提供的1-环丙基-6-氟-4-氧代-7-(哌嗪-1-基)-1,4-二氢喹啉-3-羧酸 MBC(PB00748-1g) 性能卓越，竭诚为您服务。
| 英文名称* | Ciprofloxacin |
|---|---|
| 中文名称 | 1-环丙基-6-氟-4-氧代-7-(哌嗪-1-基)-1,4-二氢喹啉-3-羧酸 |
| 别名 | Bay-09867, Bay o 9867, Ciprobay, Ciproxan |
| 产品描述 | Ciprofloxacin, a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria. |
| 靶点活性 | Topo II Topo IV |
| 体内活性 | Ciprofloxacin (1 mg/L) induces GST activity, in contrast with inhibited GST and CAT of larvae exposed to enrofloxacin. Ciprofloxacin (≥10 μg/L) and enrofloxacin are ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae[4]. Ciprofloxacin (CIP) shows potent activity against Y. pestis with MIC90 of 0.03 μg/mL[2]. In a murine model of pneumonic plague, ciprofloxacin (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in humans following a 500 mg dose of oral ciprofloxacin. Intraperitoneal ciprofloxacin reduces the lung bacterial load compared to controls treated with intraperitoneal PBS[5]. |
| CAS | 85721-33-1 |
| 纯度 | 98% |
| 分子量 | 331.34 |
| 分子式 | C17H18FN3O3 |
| 溶解度 | DMSO: Insoluble Water: Insoluble ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| 储存温度 | 0-4℃ for short term (days to weeks), or -20℃ for long term (months). |
| 品牌 | MBC |
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